The patient had run out of treatment options. Her cancer, a rare form of sarcoma, had metastasized and was no longer responding to therapies. As a next step, doctors at the Washington University School of […]
Changes in Metabolism Help Melanomas Spread
Melanoma, the deadliest form of skin cancer, can be treated effectively through surgery when it’s caught early. But once it has spread from the original site of the tumor to other organs […]
Maintenance Therapy with CC-486 Extends Survival of Adults with AML
An investigational drug extended survival of adults with the blood cancer acute myeloid leukemia (AML), according to results from a large clinical trial. The drug, CC-486, is related to another therapy called azacitidine (Vidaza). […]
Prostate Cancer Prevention and Finasteride: A Conversation with NCI’s Dr. Howard Parnes
What was the rationale for testing finasteride as a way to prevent prostate cancer? Finasteride blocks the activity of an enzyme called 5-alpha reductase. This enzyme converts the hormone testosterone into dihydrotestosterone, […]
Whole- and Partial-Breast Radiation Effective at Preventing Breast Cancer from Returning
New results from two clinical trials suggest that either of two types of radiation therapy after breast-conserving surgery for women with early-stage breast cancer can reduce the risk of the cancer returning. In the randomized clinical […]
Cancer Control in American Indian and Alaska Native Populations: A Conversation with Dr. Shobha Srinivasan
What are some examples of the cancer disparities among American Indian and Alaska Native people? AI/AN populations have the lowest survival rates for nearly all types of cancer of any subpopulation in […]
Moving Beyond BMI: Low Muscle Mass May Affect Cancer Survival
For some women diagnosed with breast cancer, low muscle mass may be linked with a poor long-term prognosis, a new study has found. In one of the largest investigations of its kind conducted […]
For Metastatic HER2-Positive Breast Cancer, New Treatments Emerge
Two new treatment options are emerging for women with metastatic breast cancer, following positive results from clinical trials. The trials tested the drugs tucatinib and trastuzumab deruxtecan (Enhertu) in women who had […]